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LC downregulation of CaMKII pathway. (a) LC treatments decreased CaMKII-positive cell number and its α phosphorylated form after 72 h of stimuli: this effect was more marked for the 5 mM LC dose. The quantified signal was normalized for the total nuclei number. (b) Representative Western blot and relevant quantification: LC stimuli for 72 h promote CaMKII α isoform activation. Data are expressed as fold changes (FC) of mean ± SD. Significance: ∗p ≤ 0.05 vs. CONTR.
