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. 2018 Dec 3;115(51):13075–13080. doi: 10.1073/pnas.1809681115

Fig. 5.

Fig. 5.

FSIP1 silencing enhances AMPK activation but reduces mTOR and β-catenin activation and mitochondrial biogenesis in TNBC cells. (A and B) Western blots showing total and phosphorylated AMPK and mTOR levels in control (Ctl) and shFSIP1 MDA-MB-231 and MDA-MB-468 cells. (C) Western blots showing expression of β-catenin signaling molecules in Ctl and shFSIP1 MDA-MB-231 cells. (D) Extracellular flux analysis of mitochondrial OCRs in Ctl and shFSIP1 MDA-MB-231 cells. Data are representative images or expressed as mean ± SEM; *P < 0.05, **P < 0.01.