Skip to main content
. 2018 Dec 17;7:e43224. doi: 10.7554/eLife.43224

Figure 5. Model of the parasite survival and immune evasion mediated by EBA-175.

Figure 5.

(A) Merozoite (purple) secretes EBA-175 to the apical end for engagement of GpA. (B) Post invasion, EBA-175 is cleaved from the surface and shed. (C) Shed EBA-175 diffuses to neighboring RBCs and engages GpA resulting in RBC recruitment and red cell clustering (D). (E) RBC clustering enables daughter merozoites easy access to an uninfected RBC for the next round of invasion. Gray arrow indicates progression through one round of invasion and replication.