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. 2018 Dec 19;7:F1000 Faculty Rev-1953. [Version 1] doi: 10.12688/f1000research.15659.1

Table 2. Different rates of Propionibacterium acnes antibiotic resistance in acne patients in different countries.

Study Country, date Patients with
acne, number
Any antibiotic
resistance, n (%)
Clindamycin
resistance,
n (%)
Erythromycin
resistance, n (%)
Azithromycin
resistance,
n (%)
Oxytetracycline
resistance, n (%)
Doxycyline
resistance, n (%)
Minocycline
resistance, n (%)
Moon 59 Korea, 2011 100
(30 P. acnes
strains isolated)
11 (36.7) 9 (30) 8 (26.7) NS 1 (3.3) 2 (6.7) 3 (10)
Coates 50 UK, 1991–2000 4,274 34.5% in 1991
55.5% in 2000
1997: ~48% 1997: 57.6% NR 1991: 12.5%
1998: 29.9%
NR NR
1997 72 72 (100) 65 (90.3) 68 (94.4) NR 38 (52.8) NR NR
Mendoza 52 Colombia, 2005,
2006
100 40% 15% 35% NS 8% 9% 1%
Gonzalez 53 Northern Mexico,
2010
49 37 (75.5) 36% 46% 82% 14% 20% 0
Luk 54 Hong Kong, 2009 111
( P. acnes isolated
from 86 patients)
47 (54.7) (53.5) 18 (20.9) NS 14 (16.3) 14 (16.3) 14 (16.3)
Abdel-Fattah 55 Egypt, 2011–2012 115
( P. acnes isolated
from 98 patients)
NR 65 (66.3) 48 (49) 5 (5.1) 18 (18.4) 6 (6.1) NS
Ross 51 1999–2001 622
UK NR 50% 50% NS 26% NR 0
Greece NR 75% 75% NS 7% NR 0
Hungary 51% 45% 45% NS 0 NR 0
Italy NR 58% 58% NS 0 NR 0
Spain 94% 91% 91% NS 5% NR 0
Sweden NR 45% 45% NS 15% NR 0
Dumont 56 France, 2010 273 NR NS 205 (75.1) NS 26 (9.5) 26 a NS

Sampling only from closed comedones. aOnly the strains resistant to tetracycline (26 patients) were tested with doxycycline. NR, not reported; NS, not studied. From Dessinioti and Katsambas 52. Reprinted with permission from Elsevier.