Table 2. Different rates of Propionibacterium acnes antibiotic resistance in acne patients in different countries.
| Study | Country, date | Patients with
acne, number |
Any antibiotic
resistance, n (%) |
Clindamycin
resistance, n (%) |
Erythromycin
resistance, n (%) |
Azithromycin
resistance, n (%) |
Oxytetracycline
resistance, n (%) |
Doxycyline
resistance, n (%) |
Minocycline
resistance, n (%) |
|---|---|---|---|---|---|---|---|---|---|
| Moon 59 | Korea, 2011 | 100
(30 P. acnes strains isolated) |
11 (36.7) | 9 (30) | 8 (26.7) | NS | 1 (3.3) | 2 (6.7) | 3 (10) |
| Coates 50 | UK, 1991–2000 | 4,274 | 34.5% in 1991
55.5% in 2000 |
1997: ~48% | 1997: 57.6% | NR | 1991: 12.5%
1998: 29.9% |
NR | NR |
| 1997 | 72 | 72 (100) | 65 (90.3) | 68 (94.4) | NR | 38 (52.8) | NR | NR | |
| Mendoza 52 | Colombia, 2005,
2006 |
100 | 40% | 15% | 35% | NS | 8% | 9% | 1% |
| Gonzalez 53 | Northern Mexico,
2010 |
49 | 37 (75.5) | 36% | 46% | 82% | 14% | 20% | 0 |
| Luk 54 | Hong Kong, 2009 | 111
( P. acnes isolated from 86 patients) |
47 (54.7) | (53.5) | 18 (20.9) | NS | 14 (16.3) | 14 (16.3) | 14 (16.3) |
| Abdel-Fattah 55 | Egypt, 2011–2012 | 115
( P. acnes isolated from 98 patients) |
NR | 65 (66.3) | 48 (49) | 5 (5.1) | 18 (18.4) | 6 (6.1) | NS |
| Ross 51 | 1999–2001 | 622 | |||||||
| UK | NR | 50% | 50% | NS | 26% | NR | 0 | ||
| Greece | NR | 75% | 75% | NS | 7% | NR | 0 | ||
| Hungary | 51% | 45% | 45% | NS | 0 | NR | 0 | ||
| Italy | NR | 58% | 58% | NS | 0 | NR | 0 | ||
| Spain | 94% | 91% | 91% | NS | 5% | NR | 0 | ||
| Sweden | NR | 45% | 45% | NS | 15% | NR | 0 | ||
| Dumont 56 | France, 2010 | 273 | NR | NS | 205 (75.1) | NS | 26 (9.5) | 26 a | NS |
Sampling only from closed comedones. aOnly the strains resistant to tetracycline (26 patients) were tested with doxycycline. NR, not reported; NS, not studied. From Dessinioti and Katsambas 52. Reprinted with permission from Elsevier.