Table 2.
Median survival estimates and survival ratios from the model
| Year of detection of metastatic disease |
||||
|---|---|---|---|---|
| Outcome | 1980 | 1990 | 2000 | 2010 |
| Median survival after recurrence (95% CI) (all), mo | 20.2 (16.5 to 24.6) | 21.2 (18.2 to 24.7) | 26.2 (22.7 to 30.4) | 38.0 (30.5 to 47.3) |
| Survival ratio (95% CI) relative to previous decade | NA | 1.05 (0.91 to 1.22) | 1.24 (1.16 to 1.32) | 1.45 (1.21 to 1.73) |
| Median survival after recurrence (95% CI) (ER+), mo | 29.1 (16.7 to 50.7) | 31.6 (23.3 to 42.7) | 39.4 (29.5 to 52.5) | 56.5 (36.6 to 87.3) |
| Survival ratio (95% CI) relative to previous decade | NA | 1.08 (0.66 to 1.79) | 1.25 (1.05 to 1.49) | 1.44 (0.93 to 2.21) |
| Median survival after recurrence (95% CI) (ER–), mo | 14.8 (8.2 to 26.8) | 14.1 (10.5 to 19.0) | 18.4 (13.6 to 24.8) | 32.6 (20.7 to 51.4) |
| Survival ratio (95% CI) relative to previous decade | NA | 0.95 (0.55 to 1.66) | 1.30 (1.08 to 1.57) | 1.77 (1.13 to 2.79) |
| Median survival after de novo stage IV (95% CI) (all), mo | 18.9 (15.1 to 23.5) | 19.5 (16.1 to 23.8) | 23.1 (19.0 to 28.0) | 31.0 (24.3 to 39.4) |
| Survival ratio (95% CI) relative to previous decade | NA | 1.04 (0.92 to 1.17) | 1.18 (1.13 to 1.23) | 1.34 (1.16 to 1.55) |
*CI = confidence interval.