Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Dec 18;12:113. doi: 10.3389/fncir.2018.00113

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Trudeau and El Mestikawy.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

The co-expression of two vesicular neurotransmitter transporters by a single neuron generates multiple signaling possibilities. (A,B) Two different vesicular neurotransmitter transporters (VNT1 or VNT2) can either be addressed to the same synaptic vesicles (SVs) or segregated in different SVs. In the first case the two transmitters (NT1 and NT2) will be coreleased simultaneously, in the second one they can be differentially released. (C) Within a neuron, two different VNTs can be targeted the same or to different varicosities. With these two options, a neuron can release two different NTs from various varicosities or corelease two NTs from a single varicosity.