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. 2018 Dec 18;9:1479. doi: 10.3389/fphar.2018.01479

FIGURE 3.

FIGURE 3

Dendrobium nobile Lindl. alkaloids (DNLA) decreased the expression of intracellular Aβ1-42 of hippocampi in 13-month-old APP/PS1 mice. (A) The sections of the hippocampi were stained with fluorescent dye Thioflavin-T. (B) Hippocampal tissue was analyzed by double- immunofluorescence through LAMP2 and Aβ1-42. (C) Immunoblot analyses of Aβ1-42 and Aβ1-40. Data were presented as mean ± S.E.M. (n = 5). ∗p < 0.05 vs. WT group, #p < 0.05 vs. APP/PS1 group. (D) Quantification of amyloid fiber plaques described in A. Data were presented as mean ± S.E.M. (n = 3). (E) Quantification of intracellular Aβ42 described in B. Data were presented as mean ± S.E.M. (n = 3). ∗p < 0.05 vs. WT group, #p < 0.05 vs. APP/PS1 group.