Table 2.
Baseline demographic data.
| Expectorating patients | Non-expectorating patients | BAL-group | Sign. | |
|---|---|---|---|---|
| N | 105 | 30 | 39 | |
| Children (018 years) (n, %) | 42 (40.0%) | 29 (96.7%) | 29 (74.4%) | |
| Adults (≥ 18 years) (n, %) | 63 (60.0%) | 1 (3.3%) | 10 (25.6%) | |
| Gender, n male (%) | 58 (56.3%) | 18 (61.1%) | 13 (33.3%) | |
| Age (mean, ± SD) | 23.9 (± 11.6) | 9.2 (± 4.8) | 13.4 (±10.3) | p = 0.000 |
| BMI (mean, ± SD) | 20.2 (± 3.4) | 16.7 (± 2.8) | 17.4 (± 3.3) | p = 0.000 |
| FEV1 (%pred) (mean, ± SD) | 70.8 (± 24.8) | 94.4 (± 13.9) | 63.1 (± 25.5) | p = 0.000 |
| FVC (%pred) (mean, ± SD) | 86.0 (± 18.0) | 95.9 (± 12.1) | 77.7 (± 23.4) | p = 0.004 |
| CF mutation | ||||
| Homozygous F508del | 49 | 8 | 26 | |
| Other mutationsa | 56 | 22 | 13 | |
BAL-group, patients requiring clinically indicated bronchoscopy; Sign., significance level; BMI, Body Mass Index; FEV1, Forced Expiratory Volume in 1 second; FVC, Forced Vital Capacity;
a
Heterozygous F508del or Other/Other. Bold values indicates significant difference between the three groups.