Figure 3.
Prophylactic administration of SCIgA/M preparation promotes mouse survival. Time-dependent follow-up of mice infected with 2 × 106 St post-prophylactic treatment (24 and 8 h) with oral delivery of the SCIgA/M preparation. Each depicted curve represents one individual mouse analyzed for weight loss (A) and disease scores (B). Sacrifice (depicted by a †) of mice having lost ≥20% of their initial weight was done to comply with the Veterinary Office's permit to conduct animal experiments. Each panel compiles the results of 2 independent experiments. (C) Survival curves resulting from the compilation of all mice in either the St alone group (red circles) or the prophylactically treated (SCIgA/M, St) group (green circles). **p < 0.01.