Table 4. Two one-sided T-test and 90% confidence interval (CI) results of the parameters after a single intramuscular administration of test formulation and reference formulation.
Parameters | t1 | t2 | 90%CI (%) |
Ratio (T/R) (%) |
Acceptable Range (%) |
---|---|---|---|---|---|
AUC0-t | 3.62a) | 2.48a) | 92.3–117.3 | 99.3 | 80–125 |
AUC0-∞ | 3.48a) | 2.41a) | 92.1–117.9 | 99.3 | 80–125 |
Cmax | 5.67a) | 4.59a) | 93.1–116.3 | 98.6 | 70–143 |
T(1–0.05)(22)=1.717. a) P<0.05.