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. 2018 Dec 21;24(47):5403–5414. doi: 10.3748/wjg.v24.i47.5403

Table 6.

Mortality

Valid No. Alive
Dead
P value
Number % Number %
Patients 100 90.12 11 9.9
Male gender 111 47 38 38.03 9 81.8 0.005
Ambulatory 104 75 74 77.93 1 10.0 0.000
CDI risk factors
Prior hospitalization 111 80 69 69.03 11 100.0 0.030
Antibiotics use 108 89 81 82.73 8 80.0 0.834
PPI usage 110 37 31 31.33 6 54.5 0.122
Chemotherapy 111 19 19 19.03 0 0.0 0.112
IBD 111 20 20 20.03 0 0.0 0.101
Steroid usage 111 17 16 16.03 1 9.1 0.546
Fever 76 21 15 23.13 6 54.5 0.031
Severe 110 20 13 13.03 7 63.6 0.000
Adverse events 107 19 15 15.53 4 40.0 0.053
Route
Lower GI 111 50 44 44.03 6 54.5 0.023
Upper GI1 24 19 19.03 5 45.5
Capsules 37 37 37.03 0 0.0
0-1 previous CDI 107 24 19 19.83 5 45.5 0.053
2+ previous CDI 83 77 6
Indication 111 0.306
Refractory 23 19 19.03 4 36.4
Recurrent 82 76 76.03 6 54.5
Prior therapy
Metronidazole 110 89 80 80.83 9 81.8 0.936
Vancomycin 110 109 98 99.03 11 100.0 0.738
Combination 109 31 25 25.53 6 54.5 0.043
Outcomes
Adverse events 107 19 15 15.53 4 40.0 0.053
Response to FMT 111 94 88 88.03 6 54.5 0.003
Mean SD Mean SD Sigma
Age (yr) 111 62.37 21.656 84 5.797 0.000
Charlson comorbidity score 81 4.57 2.98 8 2.4 0.001
Previous CDI episodes (n) 107 2.57 1.633 1.45 1.368 0.025
Time from 1st CDI (d) 89 138.47 197.991 110.75 63.036 0.493
Creatinine (mg/dL) 76 1.44 1.507 1.74 1.193 0.482
Albumin (mg/L) 54 3.34 0.782 2.4 0.408 0.010
WBC (103/dL) 76 13.65 18.87 15.64 78.62 0.564
1

Upper GI: Gastroscopy, nasogastric tube or through percutaneous endoscopic gastrostomy;

2

Percentages refer to the total number of subjects in the cohort;

3

Percentages refer to the number of subjects in the specific group. CDI: Clostridium difficile infection; IBD: Inflammatory bowel diseases; PPI: Proton pump inhibitor; GI: Gastrointestinal; FMT: Fecal microbiota implantation; IQR: Inter quartile range; WBC: White blood cells; Prior hospitalization: Hospitalization within the 3 mo prior to the FMT; Prior hospitalization: Antibiotics use in the 3 mo prior to the FMT.