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. 2018 Dec 18;9:1081. doi: 10.3389/fneur.2018.01081

Figure 1.

Figure 1

Monocytes in the peripheral blood and cerebrospinal fluid. The proportion of monocytes in relation to total leukocytes was determined in the peripheral blood (PB, closed symbols, white background) and cerebrospinal fluid (CSF, open symbols, gray background) from healthy elderly controls (n = 13; blue circles) and PD patients (n = 10; red triangles). While the proportion of total monocytes did not differ between study groups, monocyte subgroup analysis based on expression of the surface marker CD16 demonstrated a highly significant decrease of classical monocytes (CD14+CD16) and a concomitant highly significant increase of non-classical monocytes (CD14+CD16+). For statistical analysis, the Mann-Whitney test was performed (***p < 0.001).