Table 4.
Data and statistical interpretations of investigation
| RA patients | Healthy individuals | p-value | |
|---|---|---|---|
| Mean ±SD | |||
| Treg percentage | 1.58 ±0.24 | 1.85 ±0.3 | ** |
| Serum IL-6 (pg/ml) | 28.1 ±9.1 | 4.2 ±0.8 | *** |
| Serum TGF-β1 (ng/ml) | 41.2 ±10.43 | 29.8 ±8.96 | *** |
| mRNA expression in PBMCs (fold change) | Mean ±SEM | ||
| IL-6 | 1.3 ±0.21 | 0.57 ±0.21 | *** |
| TGF-β1 | 1.35 ±0.24 | 2.15 ±0.37 | ** |
| Correlation | Correlation coefficient (r) | ||
| Tregs (%) and serum IL-6 | 0.47 | ** | |
| Tregs (%) and IL-6 expression in PBMCs | 0.37 | ** | |
**
p < 0.01
***
p < 0.001