Table 4.
Differences in CDs markers of B and T lymphocytes and natural killer cells between different age groups of Down syndrome and control groups
| CD markers | Group I | Group II | Group III | Group IV | ||||
|---|---|---|---|---|---|---|---|---|
| DS (n = 25) | CG (n = 22) | DS (n = 75) | CG (n = 35) | DS (n = 38) | CG (n = 32) | DS (n = 12) | CG (n = 11) | |
| CD3 | 1450.8 ±324.49 | 2545 ±346.38 | 1161.47 ±374.25 | 2624.86 ±524.3 | 1107.37 ±295.85 | 1949.38 ±398.19 | 1315.83 ±311.96 | 1610.91 ±370.42 |
| t-value | 11.177 | 14.842 | 9.883 | 2.073 | ||||
| p-value | < 0.001* | < 0.001* | < 0.001* | 0.051 | ||||
| CD4 | 668 ±139.46 | 1447.73 ±191.78 | 500.93 ±164.84 | 1521.43 ±353.82 | 460 ±159 | 1097.81 ±245.45 | 574.17 ±168.28 | 892.73 ±225.79 |
| t-value | 16.074 | 16.26 | 12.636 | 3.859 | ||||
| p-value | < 0.001* | < 0.001* | < 0.001* | < 0.001* | ||||
| CD8 | 782.8 ±226.23 | 1120 ±241.31 | 657.87 ±236 | 1100.57 ±203.82 | 650 ±183.76 | 845.31 ±168.18 | 750 ±182.16 | 718.18 ±158.54 |
| t-value | 4.942 | 9.554 | 4.604 | 0.445 | ||||
| p-value | < 0.001* | < 0.001* | < 0.001* | 0.661 | ||||
| CD19 | 416.4 ±126.09 | 1348.18 ±345.96 | 412.13 ±116.15 | 1256 ±134.58 | 423.95 ±116.98 | 783.13 ±79.25 | 165.83 ±114.13 | 540 ±53.1 |
| t-value | 11.953 | 33.72 | 15.228 | 9.919 | ||||
| p-value | < 0.001* | < 0.001* | < 0.001* | < 0.001* | ||||
| CD56 | 185.6 ±76.33 | 954.55 ±316.95 | 230.67 ±91.18 | 476 ±43.33 | 231.84 ±96.89 | 475.31 ±95.71 | 259.17 ±63.6 | 984.55 ±151.42 |
| t-value | 11.1 | 19.128 | 10.531 | 15.22 | ||||
| p-value | < 0.001* | < 0.001* | < 0.001* | < 0.001* | ||||
t – independent t test;
*
p-value significant ≤ 0.05