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. 2018 Dec 18;9:2896. doi: 10.3389/fimmu.2018.02896

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Copyright © 2018 Kuo, Teoh, Tuong, Leggatt, Mattarollo and Frazer.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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K14.E7xRb ^ΔL/ΔL and non-transgenic mice respond equally to intradermal immunization. OVA specific CD8 T cell responses in the draining LN following intradermal immunization were assessed as IFNγ production following in vitro peptide re-stimulation. (A) Representative FACS plots pre-gated on TCRβ+ CD8 T cells showing IFNγ production with (+) or without (-) SIINFEKL re-stimulation. (B) Quantitative result showing mean ± SEM with n > 3 for each mouse type. Open circle, without stimulation; closed circle, with stimulation. Analyses were done using one-way ANOVA, with Bonferroni's multiple comparison tests. Result significance was shown, where ^*p < 0.05, ^***p < 0.001, and ^****p < 0.0001.