Table 1.

Variant calls for the two Fanconi anemia (FA) and two FANCD2 RV‐corrected FA samples, with respect to the human reference genome

Variant type	Sample	Sample type	Variant count
			No.	Repeated in replicates	Repeated in all samples
INDEL	GRL1398	FA	28,053	19,556	15,023
	GRL1399	FA	27,218
	GRL1400	FA_RV	27,386	18,836
	GRL1401	FA_RV	25,966
SNP	GRL1398	FA	201,940	153,043	128,179
	GRL1399	FA	198,816
	GRL1400	FA_RV	194,954	144,266
	GRL1401	FA_RV	191,593

While a significantly large number of SNPs and INDELs were found to be repeated in all four samples, the difference in the number of variants within biological replicates shows evidence of heterogeneity in these replicate cell line cultures.