Table 1.
Samples | SCZ(N = 17) vs. HC(N = 36) |
OCD(N = 35) vs. HC(N = 36) |
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---|---|---|---|---|---|---|---|---|---|---|
SCZ mean (SD) | HC mean (SD) | t/χ2/u1 | p | Cohen’s d | OCD mean (SD) | HC mean (SD) | t/χ2/u1 | p | Cohen’s d | |
Demographic and clinical variables | ||||||||||
Age (years) | 22.41 (3.74) | 22.86 (2.67) | −0.44 | 0.661 | – | 23.86 (5.48) | 22.86 (2.67) | 0.97 | 0.338 | – |
Sex (female, %) | 8 (47.1) | 23 (63.9) | 1.35 | 0.246 | – | 16 (45.7) | 23 (63.9) | 2.37 | 0.124 | – |
Education (years) | 13.76 (2.54) | 15.89 (1.91) | −3.07 | <0.01 | – | 14.96 (2.32) | 15.89 (1.91) | −1.85 | 0.069 | – |
Duration (month) | 19.94 (22.67) | – | – | – | – | 63.71 (66.94) | – | – | – | – |
Under treatment (medication, %)∗ | 11 (64.7) | – | – | – | – | 15 (42.9) | – | – | – | – |
PANSS_Total | 58.71 (12.10) | – | – | – | – | – | – | – | – | – |
PANSS_P | 17.47 (4.14) | – | – | – | – | – | – | – | – | – |
PANSS_N | 10.29 (3.55) | – | – | – | – | – | – | – | – | – |
PANSS_G | 30.94 (7.16) | – | – | – | – | – | – | – | – | – |
YBOCS_Total | – | – | – | – | – | 30.37 (6.14) | – | – | – | – |
YBOCS_O | – | – | – | – | – | 16.40 (2.77) | – | – | – | – |
YBOCS_C | – | – | – | – | – | 13.97 (4.93) | – | – | – | – |
BDI | 18.12 (9.69) | 5.69 (5.01) | 4.98 | <0.001 | – | 20.06 (9.83) | 5.69 (5.01) | 7.72 | <0.001 | – |
STAI-T | 53.00 (10.52) | 40.17 (9.08) | 4.57 | <0.001 | – | 57.91 (8.72) | 40.17 (9.08) | 8.40 | <0.001 | – |
STAI-S | 50.12 (13.72) | 41.33 (8.09) | 2.45 | <0.05 | – | 52.17 (11.52) | 41.33 (8.09) | 4.60 | <0.001 | – |
FD | 0.10 (0.06) | 0.08 (0.05) | 1.32 | 0.190 | 0.10 (0.05) | 0.08 (0.05) | 1.51 | 0.134 | – | |
Frames censored (%) | 0.02 (0.02) | 0.01 (0.03) | 1.35 | 0.183 | 0.01 (0.02) | 0.01 (0.03) | 0.67 | 0.507 | – | |
Behavioral performance during SART | ||||||||||
Omission error | 0.04 (0.04) | 0.01 (0.01) | 102.50 | <0.001 | 1.029 | 0.03 (0.04) | 0.01 (0.01) | 418.50 | <0.01 | 0.686 |
Commission error | 0.48 (0.23) | 0.30 (0.15) | 3.02 | <0.01 | 0.927 | 0.40 (0.25) | 0.30 (0.15) | 2.18 | <0.05 | 0.485 |
Mean RT (ms) | 401.62 (77.05) | 402.94 (93.34) | −0.05 | 0.960 | – | 393.48 (104.64) | 402.94 (93.34) | −0.40 | 0.689 | – |
IIV | 0.34 (0.08) | 0.23 (0.06) | 5.47 | <0.001 | 1.556 | 0.29 (0.12) | 0.23 (0.06) | 2.68 | <0.01 | 0.632 |
∗The notion that patients were not under medication treatment means that the patients were medication-naïve, or they did not take any antipsychotic meds at least for 3 months prior to the day when they were enrolled. SCZ, schizophrenia; OCD, obsessive-compulsive disorder; HC, healthy controls; SART, sustained attention to response task; SD: standard deviation; YBOCS, Yale-Brown Obsessive-Compulsive Scale; PANSS, Positive and Negative Syndrome Scale; BDI, Beck Depression Inventory; STAI, State Trait Anxiety Inventory; RT, reaction time; IIV, intra-individual variation; FD, frame-wise displacement. 1Comparison results of age, education, commission error, mean RT, IIV, FD and frames censored were indicated by t; results of sex were indicated by χ2; comparison results of omission error were indicated by u.