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. 2018 Dec 19;12:319. doi: 10.3389/fnbeh.2018.00319

Table 2.

Brain regions showing functional connectivity differences based on default mode network seeds among SCZ and OCD in comparison with HC.

Brain regions Direction Voxel Peak coordinates (x/y/z; MNI) Peak T values Cohen’s d
SCZ vs. HC
PCC as seed None
Left mPFC as seed
Bilateral anterior cingulum cortex (BA32, 24) SCZ < HC 205 12 24 33 3.75 1.12
Right mPFC as seed
Bilateral amygdala extending to striatum (BA48, 34) SCZ < HC 351 −3 −12 −3 4.55 1.36
OCD vs. HC
PCC as seed None
Left mPFC as seed None
Right mPFC as seed
Left superior frontal gyrus (BA9) OCD < HC 163 −12 54 45 4.90 1.47
Bilateral thalamus OCD < HC 163 9 −15 6 4.24 1.27

SCZ, schizophrenia; OCD, obsessive-compulsive disorder; HC: healthy control; mPFC, medical prefrontal cortex; PCC, posterior cingulate cortex; BA, Broadmann area; x, y, z, coordinates of peak locations in the Montreal Neurological Institute space (MNI). Significance threshold was set at p < 0.05, FDR cluster level corrected, starting from voxel level p < 0.005 uncorrected.