Table 3.
Phylum | Family | Genus | Number of OTUs | ASD | HCs |
---|---|---|---|---|---|
Actinobacteria | Actinomycetaceae | Actinomyces | 1 | 0.002 ± 0.001 | 0.039 ± 0.02 |
Corynebacteriaceae | Corynebacterium | 1 | 0.001 ± 0.001 | 0.021 ± 0.007 | |
Bifidobacteriaceae | Bifidobacterium (longum) | 1 | 6.904 ± 2.021 | 15.302 ± 2.943 | |
Coriobacteriaceae | – | 1 | 0 | 0.026 ± 0.016 | |
Coriobacteriaceae | Eggerthella (lenta) | 1 | 0.081 ± 0.031 | 0.408 ± 0.113 | |
Bacteroidetes | Porphyromonadaceae | Parabacteroides (distasonis) | 1 | 0.043 ± 0.028 | 0 |
Bacteroidaceae | Bacteroides | 22 | 1.606 ± 1.121 | 0.003 ± 0.002 | |
Firmicutes | Aerococcaceae | – | 1 | 0.006 ± 0.002 | 0.059 ± 0.027 |
Streptococcaceae | Streptococcus | 5 | 0.065 ± 0.03 | 0.704 ± 0.176 | |
U. Clostridiales | – | 3 | 0.09 ± 0.05 | 0.1 ± 0.07 | |
– | 2 | 0.16 ± 0.15 | 0 | ||
Ruminococcus | 3 | 0.42 ± 0.19 | 0.04 ± 0.02 | ||
Lachnospiraceae | Blautia | 10 | 1.06 ± 0.38 | 2.99 ± 0.55 | |
Coprococcus | 4 | 0.06 ± 0.02 | 0.3 ± 0.08 | ||
Lachnospira | 1 | 0.04 ± 0.03 | 0 | ||
Roseburia | 1 | 0.06 ± 0.05 | 0 | ||
Peptostreptococcaceae | – | 1 | 0.02 ± 0.02 | 0 | |
– | 18 | 0.97 ± 0.36 | 0.1 ± 0.02 | ||
Ruminococcaceae | Faecalibacterium (prausnitzii) | 6 | 0.51 ± 0.31 | 0.04 ± 0.01 | |
Oscillospira | 3 | 1.21 ± 0.5 | 0.15 ± 0.05 | ||
Proteobacteria | Enterobacteriaceae | – | 4 | 0.407 ± 0.368 | 0.002 ± 0.002 |
Pasteurellaceae | – | 1 | 0.057 ± 0.049 | 0 |
Discriminant OTUs were identified using LEfSe algorithm and Metastats comparison (p < 0.05 for Metastats comparison and LDA > 2 with alpha < 0.05 for LEfSe). Mean ± SEM of key OTUs with relative abundance > 0.01% is reported. A more detailed table with average and SEM for each discriminatory OTU is provided as Supplementary Table S1.