Table 3.
The result of MIC test for plants and the determined synergistic effect
| Plant/drug | Individual MIC of plant extract (µg/ml) | Combination MIC (µg/ml) | Combined FIC index (µg/ml) | Synergy |
|---|---|---|---|---|
| B. serrata/EMB | 125.0 | 62.50 | 0.500 | Sy |
| L. stoechas/EMB | 250.0 | 31.30 | 0.125 | Sy |
| D. stramonium/EMB | 375.0 | 46.88 | 0.125 | Sy |
| T. vulgaris/EMB | 500.0 | 250.00 | 0.500 | Sy |
| R. officinalis/EMB | 187.5 | 31.30 | 0.166 | Sy |
| B. serrata/INH | 125.0 | 31.30 | 0.250 | Sy |
| L. stoechas/INH | 250.0 | 62.50 | 0.250 | Sy |
| D. stramonium/INH | 375.0 | 250.00 | 0.660 | N |
| T. vulgaris/INH | 500.0 | 125.00 | 0.250 | Sy |
| R. officinalis/INH | 187.5 | 125.00 | 0.660 | N |
EMB, ethambutol; INH, isoniazid; MIC, minimum inhibitory concentration; FIC, fractional inhibitory concentration; Sy, synergistic; N, no interaction