Table 3.
Comparison between candidate miRNA expression rates (mean of ΔCt ± SD) according to the clinicopathological characteristics of GC patients
| Variable | N | miR-21 | miR-25 | miR-93 | miR-106b | ||||
|---|---|---|---|---|---|---|---|---|---|
| Mean ± SD | P value | Mean ± SD | P value | Mean ± SD | P value | Mean ± SD | P value | ||
| Age | |||||||||
| >50 | 64 | 3.20 ±2.76 | 0.0893 | 4.175 ± 3.166 | 0.6344 | 6.36 ± 5.176 | 0.0581 | 6.35 ±5.08 | 0.175 |
| <50 | 50 | 5.79 ±4.25 | 5.46 ± 5.038 | 6.32 ± 5.32 | 6.32 ± 5.34 | ||||
| Sex | |||||||||
| Male | 65 | 4.750 ± 3.166 | 0.6654 | 5.33 ± 4.38 | 0.270 | 6.45 ± 5.031 | 0.270 | 6.886 ± 6.36 | 0.270 |
| Female | 49 | 5.038 ± 5.46 | 5.91 ± 4.16 | 5.991± 4.754 | 3.195 ±2.98 | ||||
| TNM | |||||||||
| I, II | 14 | 1.048 ± 1.009 | 0.0309 | 5.59 ± 3.38 | 0.0253 | 4.171 ± 3.521 | 0.5830 | 8.137 ± 7.93 | 0.0138 |
| III, IV | 20 | 5.036 ± 4.070 | 3.280 ±2.524 | 4.843 ± 3.524 | 4.62 ±3.905 | ||||
| LNM | |||||||||
| Positive | 18 | 4.62 ± 4.43 | 0.0259 | 4.62 ±4.43 | 0.0439 | 6.848 ±5.094 | 0.0402 | 3.21 ± 1.32 | 0.0070 |
| Negative | 20 | 4.38 ± 2.635 | 4.38 ±2.63 | 3.427 ±2.327 | 3.169± 2.138 | ||||
| H. Pylori | |||||||||
| Positive | 64 | 4.835 ± 2.935 | 0.0014 | 3.624 ± 3.28 | 0.0128 | 4.865 ± 4.524 | 0.2313 | 7.34 ±6.92 | 0.0023 |
| Negative | 32 | 1.635 ± 1.122 | 6.134 ± 5.35 | 3.427 ± 2.124 | 6.21 ± 4.724 | ||||