Fig. 5.
The process of the microchannel formation inside the gel using the 3D printing of sacrificial materials (SM). At first, a computer-based plan of a SM is fabricated using the 3D printing. Then this 3D construct was immersed in a solution of an appropriate biomaterial and certain cells. After gelation of the biomaterial, the 3D constructs were immersed in culture media, which flows inside the channel, dissolves SM, and creates microchannel within the scaffolds.