Table 2.

Comparison of HrQoL between patients with MSA‐P and MSA‐C

	MSA	MSA‐P	MSA‐C	P value	P' valuea
SF‐36 domains
SF‐36 total	87.71 ± 16.98	84.05 ± 16.33	94.24 ± 16.32	0.001	0.006
Physical component summary	39.13 ± 15.47	36.58 ± 16.41	44.08 ± 12.06	0.001	0.017
Mental component summary	39.57 ± 17.20	36.20 ± 17.56	46.23 ± 14.44	0.000	0.001
Physical function PF	15.41 ± 5.42	15.00 ± 5.05	16.15 ± 6.01	0.516	0.767
Role physical RP	4.13 ± 0.66	4.16 ± 0.76	4.07 ± 0.44	0.442	0.212
Bodily pain BP	9.96 ± 2.73	9.41 ± 2.88	10.85 ± 2.26	0.002	0.015
General health GH	14.21 ± 2.73	13.80 ± 2.70	14.93 ± 2.65	0.007	0.047
Vitality VT	14.26 ± 4.50	13.40 ± 4.25	15.78 ± 4.59	0.004	0.007
Social function SF	5.49 ± 2.22	5.16 ± 2.17	6.09 ± 2.19	0.017	0.081
Role emotion RE	4.96 ± 1.34	4.71 ± 1.39	5.41 ± 1.11	0.004	0.006
Mental health MH	19.49 ± 5.44	18.67 ± 5.26	20.96 ± 5.52	0.022	0.028
EQ‐5D domains
EQ‐5D total	9.01 ± 1.83	9.33 ± 1.76	8.43 ± 1.83	0.002	0.037
Mobility	2.08 ± 0.50	2.09 ± 0.50	2.07 ± 0.49	0.821	0.632
Self‐care	1.95 ± 0.62	2.04 ± 0.62	1.78 ± 0.59	0.026	0.076
Usual activities	2.08 ± 0.51	2.10 ± 0.54	2.04 ± 0.47	0.546	0.898
Pain/Discomfort	1.43 ± 0.60	1.52 ± 0.63	1.26 ± 0.49	0.015	0.031
Anxiety/Depression	1.48 ± 0.532	1.59 ± 0.54	1.28 ± 0.46	0.002	0.002

EQ‐5D: the EuroQol instrument; HrQoL: health‐related quality of life; MSA: multiple system atrophy; MSA‐C: MSA with prominent cerebellar ataxia; MSA‐P: MSA with predominant parkinsonism; SF‐36: the Medical Outcomes Study 36‐Item Short Form.

^a P' means the comparison between MSA subtypes after adjusting disease duration by analyses of covariance (ANCOVA). Bold indicates P ＜ 0.05.