Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Differential effect of E2 and EE exposure on the production of different cytokines from LPS-activated splenic leukocytes from NZB/WF1 mice. Splenic leukocytes were activated by LPS (500 ng/mL) for 24 h. Cell culture supernatants were used for ELISA to evaluate the production of cytokines (A) IFNγ, (B) IL-1β, (C) IL-6, (D) TNFα, (E) IL-2, and (F) IL-10 with Ciraplex® multiplex cytokine assay. Data are expressed as mean ± SEM (n ≥ 4). *P < 0.05; **P < 0.01; ***P < 0.001.
