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. 2018 Oct 4;151(2):128–142. doi: 10.1093/ajcp/aqy116

Table 3 .

Current and Piecewise Regression-Derived Reference Intervals (Lower Reference Limit 2.5th Percentile Value and Upper Reference Limit 97.5th Percentile Value) for Adults Aged 20-79 Yearsa

Variable Age, y Current Reference Intervalsb Age, y Piecewise Regression-Derived Reference Intervals
RBC count, million cells/µL
 Male Adults 4.32-5.72 20-35
36-50
51-60
61-79
4.42-5.82
4.23-5.82
4.23-5.69
3.90-5.69
 Female Adults 3.90-5.03 20-79 3.72-5.20
Hemoglobin, g/dL
 Male Adults 13.5-17.5 20-35 13.5-17.5
36-55 13.5-17.3
56-79 12.4-17.3
 Female Adults 12.0-15.5 20-25 11.1-15.4
26-30 11.1-15.2
31-40
41-45
46-50
51-79
10.6-15.2
10.6-15.5
10.6-15.9
11.4-15.9
Hematocrit, %
 Male Adults 38.8-50.0 20-35
36-60
61-70
40.2-51.0
38.8-51.0
37.0-51.0
71-79 35.0-51.0
 Female Adults 34.9-44.5 20-45
46-50
32.5-45.2
32.5-46.8
51-79 34.2-46.8
Mean cell volume, fL
 Male Adults 81.2-95.1 20-50
51-79
81.2-97.3
81.2-100.0
 Female Adults 81.6-98.3 20-40
41-55
56-79
75.9-97.4
71.6-99.2
79.7-99.2
Mean cell hemoglobin, pgc
 Male 20-35
36-50
51-75
76-79
27.1-33.4
27.1-34.0
27.1-34.5
24.8-34.5
 Female 20-40
41-79
24.7-33.7
24.7-34.3
Mean cell hemoglobin concentration, g/dLc
 Male 20-55
56-79
32.4-36.0
32.4-35.7
 Female 20-60
61-79
32.1-35.8
32.1-35.6
Red cell distribution width, %
 Male Adults 11.8-15.6 20-45
46-50
51-70
71-79
11.3-13.8
11.5-13.8
11.5-14.8
11.7-14.8
 Female Adults 11.9-15.5 20-45
46-79
11.3-15.6
11.4-15.6

aData from National Health and Nutrition Examination Survey 1999 to 2012 (supplemental data).

bValues from Mayo Clinic.21

cCurrent reference intervals are not provided by Mayo Clinic.21