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. 2018 Dec 21;14:119–133. doi: 10.2147/IJN.S186899

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© 2019 Teng et al. This work is published and licensed by Dove Medical Press Limited

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Pharmaceutical characteristics of NMP-NLC in vitro.

Notes: (A) Particle size and PDI of NMP-NLC analyzed by DLS. (B) TEM morphology of NMP-NLC. Bar =50 nm. (C) In vitro drug release profile of NMP-NLC and NMP suspension in pH 1.2 simulated succus gastricus. (D) In vitro drug release profile of NMP-NLC and NMP suspension in pH 6.8 simulated intestinal fluid. (E) Particle size and PDI of NMP-NLC during 2 weeks of storage at 4°C and (F) particle size and PDI of NMP-NLC during 2 weeks of storage at 25°C. Results are expressed as the mean ± SD (n=3).

Abbreviations: NMP-NLC, nimodipine-loaded nanostructured lipid carriers; PDI, polydispersity index.