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. 2018 Dec 21;14:135–148. doi: 10.2147/IJN.S181296

Figure 3.

Figure 3

Cytotoxicity of free CTX, NPs-CTX, and FA-NPs-CTX.

Notes: (A) HeLa and (B) A549 cells were treated for 24, 48, and 72 hours with CTX formulations. Data are presented as the mean ± SD (n=6). *P<0.05 and **P<0.01 vs NPs-CTX; #P<0.05 and ##P<0.01 vs free CTX.

Abbreviations: CTX, cabazitaxel; FA, folic acid; FA-NPs-CTX, FR-targeted nanoparticles loaded with cabazitaxel; FR, folate receptor; Free CTX, cabazitaxel dissolved in ethanol; NPs-CTX, cabazitaxel-loaded nanoparticles.