Table 2.
Hemolysis ratio obtained from microplate reader at 540 nm
| 5 | 10 | 25 | 50 | 100 | 200 | |
|---|---|---|---|---|---|---|
| NPs-CTX | 0.51±0.15 | 0.60±0.15 | 0.66±0.10 | 2.13±0.15 | 6.85±0.30 | 16.13±0.15 |
| FA-NPs-CTX | 0.46±0.09 | 0.61±0.15 | 0.68±0.12 | 2.74±0.15 | 10.35±0.15 | 16.74±0.15 |
| Tween-CTX | 60.43±0.91 | 73.36±0.76 | 77.63±1.07 | 84.02±0.46 | 89.9±0.38 | 95.9±0.67 |
Note: Data are presented as mean ± SD (n=3).
Abbreviations: FA-NPs-CTX, FR-targeted nanoparticles loaded with cabazitaxel; FR, folate receptor; NPs-CTX, cabazitaxel-loaded nanoparticles; Tween-CTX, CTX dissolved in a mixture of Tween 80 and 13% ethanol (w/w) at a ratio of 1:4 (v/v).