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. 2018 Dec 21;13:153–160. doi: 10.2147/DDDT.S163197

Figure 1.

Figure 1

(A) Dexmedetomidine reduces isoflurane-induced activation of caspase-3 (17 kD). (B) Caspase-3 protein expression level in each group at 2 h, 12 h, 24 h, 3 day, 7 day and 28 day after isoflurane anesthesia. Quantification of caspase-3 is normalized to GAPDH.

Notes: *P<0.05, **P<0.01, compared with control group; #P<0.05, compared with isoflurane group (n=6). One-way ANOVA followed by Tukey’s post hoc multiple comparison tests was used for data analysis.

Abbreviations: Iso, isoflurane; Dex1, isoflurane with a single dose of dexmedetomidine; Dex2, isoflurane with dual doses of dexmedetomidine; h, hours; d, day.