Table S1.

Echo protocol

A. Views Parasternal long axis – high depth Parasternal long axis – medium depth Identify structures Assess LV size and function, RV size and function, pericardium Screen for AR and MR (with color doppler) Parasternal short axis Aortic valve level. Identification of structures Screening for TR and AR (color) Mitral valve level Papillary muscle level LV size and function RV size and function Pericardial space Apical Apical 4 chamber – high depth Screen for presence of pericardial/pleural fluid Apical 4 chamber – medium depth Identify structures LV size and function, RV size and function, pericardium RV: LV size ratio estimation Screen for TR and MR (color Doppler) Subcostal 4 chamber Identify structures LV size and function, RV size and function, pericardium RV:LV size ratio Screen for TR and MR (color) Subcostal inferior vena cava Assess IVC diameter and document respiratory variation (2D, M-mode)

B. Data points LV systolic function (ejection fraction) estimation: visual (in 5% increments) and semi-quantitative (Simpson’s method). LV systolic function categories: hyperdynamic >70, normal 55–70, mildly reduced 45–54, moderately reduced 30–44, severely reduced <30 Regional wall motion abnormalities RV function (normal, reduced) RV size (normal, dilated - mild/moderate/severe) Record valvular regurgitation (moderate, severe) – Aortic, Mitral, Pulmonary, Tricuspid valves Pericardial effusion (none, small, moderate, large) Tamponade (yes/no)

C. Quality of the study Good – All images obtained are of diagnostic value. Fair – Most views were obtained, and most of them are diagnostic Suboptimal – One or few views were obtained that are diagnostic Poor – None or few views that were obtained are diagnostic

LV, Left ventricle; RV, Right ventricle; AR, Aortic regurgitation; MR, mitral regurgitation; TR, Tricuspid regurgitation; IVC, Inferior vena cava