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. 2018 Dec 26;13(12):e0209687. doi: 10.1371/journal.pone.0209687

Table 2. Major causes of death in entire cohort and in patients with atrial fibrillation according to ICD-10 codes.

Rank Total Cohort AF patients
ICD-10 codes Number (%) ICD-10 codes Number (%)
1 Malignant neoplasms (C) 15,440 (27.6) Diseases of the circulatory system (I) 1,701 (38.0)
2 Diseases of the circulatory system (I) 12,546 (22.4) Malignant neoplasms (C) 1,046 (23.4)
3 Injury, poisoning and certain other consequences of external causes (S & T) 6,779 (12.1) Diseases of the respiratory system (J) 372 (8.4)
4 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R) 5,978 (10.7) Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R) 275 (6.2)
5 Diseases of the respiratory system (J) 3,669 (6.6) Endocrine, nutritional and metabolic diseases (E) 253 (5.7)
6 Endocrine, nutritional and metabolic diseases (E) 2,649 (4.7) Injury, poisoning and certain other consequences of external causes (S & T) 195 (4.4)
7 Diseases of the digestive system (K) 2,496 (4.5) Diseases of the digestive system (K) 156 (3.5)
8 Certain infectious and parasitic diseases (A & B) 1,332 (2.3) Diseases of the genitourinary system (N) 124 (2.8)
9 Diseases of the nervous system (G) 1,303 (2.3) Certain infectious and parasitic diseases (A & B) 108 (2.4)
10 Mental, behavioral and neurodevelopmental disorders (F) 1,025 (1.8) Diseases of the nervous system (G) 71 (1.6)

AF, atrial fibrillation; ICD, international statistical classification of diseases and related health problems.