. 2018 Oct 31;33(53):e298. doi: 10.3346/jkms.2018.33.e298

Table 1. Demographic characteristics of the patients with renal impairment classified by renal impairment severity.

Parameters	Renal impairment severity			P value^a
Parameters	Mild	Moderate	Severe	P value^a
No. of subjects	21	27	18	-
Age, yr^a	55.5 ± 13.2	65.4 ± 11.8	56.2 ± 14.7	0.018
Sex, male:female^b	16:5	19:8	11:7	0.248
Height, cm^a	167 ± 8.3	160.7 ± 6.0	162 ± 9.8	0.033
Weight, kg	70.2 ± 12.4	64.4 ± 9.0	67.3 ± 16.9	0.341
BUN, mg/dL^a	16.6 ± 3.9	19.3 ± 5.1	39.1 ± 13.4	< 0.001
Creatinine, mg/dL^a	1.0 ± 0.2	1.5 ± 0.3	3.3 ± 1.3	< 0.001
MDRD eGFR, mL/min/1.73 m^2a	70.0 ± 8.1	44.0 ± 8.2	20.9 ± 5.4	< 0.001
AST, IU/L	22.2 ± 8.8	22.4 ± 8.6	22.0 ± 8.8	0.891
ALT, IU/L	22.2 ± 14.8	21.5 ± 14.6	21.9 ± 15.0	0.577

All parameters are presented as the mean ± standard deviation.

BUN = blood urea nitrogen, MDRD = modification of diet in renal disease, eGFR = estimated glomerular filtration rate, AST = aspartate aminotransferase, ALT = alanine aminotransferase.

^aP value using one-way analysis of variance; ^bPearson's χ².