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(A) The siRNA‐mediated knockdown of CMKLR1 and CCRL2. (B) Chemerin‐induced phosphorylation of Akt and ERK was inhibited by siRNA against CMKLR1. (C) Modified Boyden chamber assay was performed with chemerin (10 nmol/L) as chemoattractant. Chemerin‐induced enhancement of migration was inhibited by siRNA against CMKLR1. Seven random microscopic fields per each well were quantified. All assays were performed in triplicate. The results are shown as the mean ± SE. *P < 0.05 versus control.
