Table 2.
Multivariable analysis for OS and EFS in CN-AML patients.
| Variables | Overall survival |
Event free survival |
||
|---|---|---|---|---|
| HR (95%CI) | P | HR (95%CI) | P | |
| PARP-1expresion (High vs Low) | 1.949 (1.384,2.745) | <0.001 | 1.822 (1.323,2.509) | <0.001 |
| Age (>60) | 2.526 (1.774,3.596) | <0.001 | 2.29 (1.648,3.182) | <0.001 |
| WBC (>10) | 1.393 (0.988,1.963) | 0.058 | 1.218 (0.883,1.679) | 0.229 |
| FLT3-ITD | 2.592 (1.744,3.852) | <0.001 | 2.108 (1.448,3.07) | <0.001 |
| NPM1 | 0.701 (0.462,1.062) | 0.094 | 0.85 (0.578,1.251) | 0.41 |
| DNMT3a | 2.029 (1.307,3.149) | 0.002 | 1.827 (1.2,2.781) | 0.005 |
| BMT | 0.493 (0.233,1.043) | 0.064 | 0.794 (0.428,1.473) | 0.464 |
| HAA treatment | 0.518 (0.313,0.858) | 0.011 | 0.576 (0.356,0.931) | 0.024 |
| IA treatment | 0.499 (0.343,0.726) | <0.001 | 0.574 (0.4,0.824) | 0.003 |