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. 2018 Nov 27;38:79–88. doi: 10.1016/j.ebiom.2018.11.030

Fig. 4.

Fig. 4

Therapeutic efficacy of MECA79-Taxol-NPs. (a) Improved efficacy in delivering Taxol to PDAC was observed in mice treated with MECA79-Taxol-NPs, as compared to no treatment, free Taxol, and Taxol-NPs (Taxol dose =0.5 mg/kg, ***p < 0.001, ANOVA, n = 5 mice/group). Arrows indicate the days of treatment. The data are presented as the mean and SEM. (b) The final weight of the tumor in mice treated with MECA79-Taxol-NPs was significantly lower, as compared to the no treatment, free Taxol, and Taxol-NP treatment groups. (*p < 0.05, **p < 0.01, ANOVA, n = 5 mice/group). The data are presented as the mean and SEM.