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. 2018 Nov 16;38:69–78. doi: 10.1016/j.ebiom.2018.11.009

Fig. 1.

Fig. 1

CHAF1A expression is elevated in GC and associated with poor clinical outcome. a–d GEO RNA sequencing database analysis of the relatively differential expression level of CHAF1A in human GC and paired adjacent normal tissues. The data were derived from the GSE29272 (a), GSE63089 (b), GSE13195 (c) and GSE2685 (d). e Relative expression levels of CHAF1A in different gastric cancer cell lines and immortalized gastric cells GES-1. *p < 0.0 5, **p < 0.01, ***p < 0.001 by Student's t-test. f The mRNA levels of CHAF1A in thirty six pairs of GC and their paired adjacent normal tissues were measured by real-time PCR (n = 36). g The protein levels of CHAF1A in five pairs of GC tissues (T) and adjacent non-tumor tissues (N) measured by western blot. h IHC staining for CHAF1A was performed on GC and adjacent normal tissues. Scale bars: 200 μm (insets 50 μm). i Kaplan-Meier analysis was performed, higher expression of CHAF1A correlated with significantly worse overall survival of GC patients (P = 1.8e-06; n = 876). The data and p-values were obtained from the Kaplan-Meier Plotter database.