Table 1.
Clinical characteristics of patients with and without NF-1.
| Characteristics | NF-1 | Non-NF-1 |
|---|---|---|
| PATIENTS | ||
| Total | 10 | 13 |
| Boys | 6 | 8 |
| Girls | 4 | 5 |
| Age at diagnosis (year), range | 3–10 | 0.8–18 |
| Follow-up months, range (mean) | 36–120 (81.6) | 12–96 (66.5) |
| PRESENTING SIGNS AND SYMPTOMS | ||
| Headache | 0 | 4 |
| Vomiting | 0 | 4 |
| Visual symptoms | 0 | 7 |
| Endocrine abnormalities | 0 | 1 |
| Proptosis | 1 | 2 |
| Nystagmus | 0 | 2 |
| Strabismus | 0 | 3 |
| Café au lait spots | 8 | 0 |
| Optic nerve pallor | 1 | 0 |
| INITIAL VISUAL FIELD (LAST VISUAL FIELD) | ||
| Normal | 7 (5) | 2 (0) |
| Monocular | 1 (2) | 1 (0) |
| Bitemporal | 1 (2) | 2 (2) |
| Nasal | 0 (0) | 1 (1) |
| Homonymous | 0 (0) | 4 (6) |
| INITIAL VISUAL ACUITY (LAST VISUAL ACUITY)† | ||
| F+F | 1 (0) | 1 (0) |
| Normal | 7 (8) | 4 (4) |
| Moderate | 0 (0) | 2 (1) |
| Poor | 1 (1) | 4 (4) |
| NLP | 1 (1) | 3 (4) |
| LOCATION OF GLIOMA | ||
| Chiasma-hypothalamus | 7 | 12 |
| Optic nerve | 8 | 3 |
| Optic tract | 4 | 3 |
| Combined | 7 | 8 |
†
Visual acuity was measured for each eye separately and converted to logMAR units and categorized as normal (logMAR ≤ 0.3, equivalent to 20/40), moderate (logMAR > 0.3 and < 1.0), poor (logMAR ≥ 1.0, equivalent to 20/200), or no light perception (NLP). In the youngest patients, visual acuity was categorized as presence or absence of fix and follow (F+F).