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Endothelial cell release of Ang-2 (A), IL-6 (B), and MIP-2 (C) into culture supernatant from WT and PD-L1−/− cell culture following a 4-h stimulation with either Thrombin (Thrmb) or TNF-α (TNF) or media Control (Ctrl). Mean±SEM, N = 5 mice/group/experiment, 3 experiments; *p < 0.05 vs. respective SH/C; @p < 0.05 vs. Control H/C. One-way ANOVA and a Tukey's Multiple comparisons test.
