Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Dec 20;5:356. doi: 10.3389/fmed.2018.00356

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Tasev, Dekker-Vroling, van Wijhe, Broxterman, Koolwijk and van Hinsbergh.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Downregulation of cell cycle genes and upregulation of metabolic genes by hypoxia. Predicted protein-protein interactions show different protein clusters. Genes that were significantly differentially regulated (FDR < 5%) in hypoxia (A,C), down-regulated (B) or upregulated in hypoxia (D) were clustered based on protein-protein interactions. The nodes represent the proteins and a shared function of the proteins are shown as interconnecting lines. The genes were clustered based on the GO (0051301) cell division pathway (A,B) or the KEGG (01100) metabolic pathway; genes involved in these pathways are indicated in red.