Table 2.
Hypoxia pathway analysis.
| Non-stimulated PB-ECFCs | VT-stimulated PB-ECFCs | |||
|---|---|---|---|---|
| Pathway name | Statistics | Pathway name | Statistics | |
| Metabolic pathways | p = 3.25e−08 | Metabolic pathways | p = 9.94e−05 | |
| Cell cycle | p = 1.78e−05 | Cell cycle | p = 0.0027 | |
| Glycolysis / Gluconeogenesis | p = 1.78e−05 | Glycolysis / Gluconeogenesis | p = 0.0088 | |
| Renal cell carcinoma | p = 0.0003 | Renal cell carcinoma | p = 2.92e−06 | |
| Glycine, serine and threonine metabolism | p = 0.0003 | Glycine, serine and threonine metabolism | p = 0.0030 | |
| TGF-beta signaling pathway | p = 0.0003 | TGF-beta signaling pathway | p = 0.0112 | |
| p53 signaling pathway | p = 0.0031 | p53 signaling pathway | p = 0.0088 | |
| Purine metabolism | p = 0.0037 | Purine metabolism | p = 0.0052 | |
| Pentose phosphate pathway | p = 0.0068 | |||
| Mucin type O-Glycan biosynthesis | p = 0.0077 | |||
| Cysteine and methionine metabolism | p = 0.0093 | |||
| Fructose and mannose metabolism | p = 0.0093 | |||
| Cytokine-cytokine receptor interaction | p = 0.0140 | Cytokine-cytokine receptor interaction | p = 4.74e−05 | |
| mTOR signaling pathway | p = 0.0167 | |||
| Adipocytokine signaling pathway | p = 0.0247 | Adipocytokine signaling pathway | p = 0.0088 | |
| Pathways in cancer | p = 0.0247 | Pathways in cancer | p = 0.0007 | |
| ECM-receptor interaction | p = 0.0338 | |||
| Ribosome | p = 0.0371 | Ribosome | p = 0.0064 | |
| PPAR signaling pathway | p = 4.74e−05 | |||
| Axon guidance | p = 0.0219 | |||
| Focal adhesion | p = 0.0450 | |||
The KEGG pathways involved in angiogenesis and metabolism with a p < 0.05 are show. Red is upregulated and green is downregulated.