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. 2018 Dec 20;8:638. doi: 10.3389/fonc.2018.00638

Table 2.

Joinpoint analysis of gastrointestinal cancers in Yangzhong, 1991–2015.

Cancer types Gender Incidence Mortality
Period EAPC (95% CI) P Period EAPC (95% CI) P
Gastric cancer Male 1991–2015 −3.0 (−3.6, −2.5) < 0.01 1991–1993 54.4 (3.1, 131.2) < 0.01
1993–2001 0.6 (−4.7, 6.2) 0.8
2001–2010 −11.9 (−15.7, −8.0) < 0.01
2010–2015 9.5 (0.1,19.9) < 0.01
Female 1991–2015 −4.5 (−5.2, −3.7) < 0.01 1991–1999 7.0 (−0.3,14.7) 0.1
1999–2011 −13.0 (−16.7,−9.1) < 0.01
2011–2015 11.3 (−9.1,36.3) 0.3
Esophageal cancer Male 1991–2005 0.2 (−1.1, 1.6) 0.7 1991–1993 49.0 (−1.9, 126.3) 0.1
1993–2000 2.6 (−4.4, 10.1) 0.4
2005–2015 −5.4 (−7.6, −3.3) < 0.01 2000–2010 −9.1 (−12.5, −5.6) < 0.01
2010–2015 4.7 (−4.6,15.6) 0.3
Female 1991–2001 −0.7 (−3.5, 2.1) 0.6 1991–1993 66.3 (5.3,162.7) < 0.01
1993–2000 0.9 (−6.6,9.0) 0.8
2001–2015 −7.7 (−9.3, −6.1) < 0.01 2000–2010 −13.9 (−17.4,−10.2) < 0.01
2010–2015 4.5 (−5.7,15.7) 0.4
Colorectal cancer Male 1991–2015 3.7 (2.2, 5.2) < 0.01 1991–2015 2.3 (0.3, 4.4) < 0.01
Female 1991–2015 1.5 (0.1, 3.0) < 0.01 1991–1993 156.1 (−18.6, 705.9) 0.1
1993–2015 −2.6 (−5.2, 0.1) 0.1

EAPC, estimated annual percent changes; CI, confidence interval.