Table 2.
Derivation Cohort: PCSK9 genotype - allele frequency and Hardy-Weinberg equilibrium.
| PCSK9 SNPs | Major (minor)allele | Minor AlleleFrequency – N (%)a | HWE P-value |
|---|---|---|---|
| A53V (rs11583680) | G (A) | 100 (14.61%) | 0.99 |
| I474V (rs562556) | A (G) | 105 (15.35%) | 0.47 |
| R46L (rs11591147) | C (A) | 7 (1.02%) | 0.98 |
Abbreviations: PCSK9: Proprotein Convertase Subtilisin/kexin type 9; SNPs: single nucleotide polymorphisms; HWE: Hardy-Weinberg Equilibrium.
a
N refers to minor allele counts in relation to the total number of alleles in the Derivation Cohort (N = 684).