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. 2018 Dec 20;9:1846. doi: 10.3389/fphys.2018.01846

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Copyright © 2018 Eusemann, Sharifi, Patt, Reinhard, Schrader, Thöne-Reineke and Petow.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Hens with follicles, estradiol-17ß concentrations, body weight and hens with foot pad dermatitis (FPD) of group “Adult”. (A) Proportion of control (blue line) and treated hens (red line) with follicles on the ovary. (B) Least squares means (LSM; continuous lines) and upper and lower bounds of the 95% confidence interval (dotted lines) of estradiol-17ß in plasma in control (blue) and treated hens (red). Missing overlap of lines indicates a significant difference (p < 0.05) between groups. (C) LSM (continuous lines) and upper and lower bounds of the 95% confidence interval (dotted lines) of body weight of control (blue) and treated hens (red). Missing overlap of lines indicates a significant difference (p < 0.01) between groups. (D) Proportion of hens with FPD of control (blue) and treated hens (red).