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. 2018 Dec 26;2(1):e201800173. doi: 10.26508/lsa.201800173

Figure 7. C/EBPα in CRC cell lines.

Figure 7.

(A) mRNA expression of CEBPA and the Wnt target AXIN2 in Caco-2 cells upon activation of Wnt signaling by inhibition of GSK3β. There is an inverse correlation between C/EBPα expression and Wnt signaling activity (AXIN2). (B) C/EBPα (red) expression levels at different Caco-2 cell differentiation steps. (C) Colony formation assay of control and doxycycline (300 ng/ml)-induced C/EBPα-expressing HCT116 cells. (D) Quantification of colony number and size showing that C/EBPα expression reduces clonogenicity and colony growth (**P < 0.01).