Table 3.

Studies Evaluating Early Detection and Intervention for Breast Cancer-Related Lymphedema

	Type of study	Year published	Patients	BCRL diagnostic technique/intervention	Results
Box et al.27	Randomized	2002	65	Circumference, bioimpedance/early physiotherapy	Early intervention reduced BCRL (30% vs. 11%)
Torres Lacomba et al.13	Randomized	2010	120	Circumference/early physiotherapy	Early intervention reduced BCRL (25% vs. 7%)
Stout et al.12	Prospective	2011	196	Perometry/compression garment	46 patients developed BCRL; 25% subclinical lymphedema, 6% advanced BCRL (Stage I/II)
Soran et al.26	Prospective	2014	186	Bioimpedance/physical therapy, compresson garment, education	33% subclinical BCRL, early intervention reduced clinical BCRL (36% vs. 4%)

BCRL, breast cancer-related lymphedema.