Table 6.
Risk factors for perioperative morbidity.
| Parameter | Complicated | Non-Complicated | OR | 95% CI | p-Value |
|---|---|---|---|---|---|
| Difficult splenectomy, n (%) | 7 (12.50%) | 49 (87.50%) | 1.69 | 0.71–4.06 | 0.234 |
| No difficult splenectomy, n (%) | 32 (7.77%) | 380 (92.23%) | |||
| Age, median years (IQR) | 40 (27–57) | 47 (29–59) | 0.99 | 0.97–1.01 | 0.162 |
| Males/Females, n (%) | 17/22 (44%/56%) | 156/273 (36%/64%) | 0.74 | 0.38–1.44 | 0.372 |
| BMI, median kg/m2 (IQR) | 27.51 (23.36–32.37) | 25.82 (22.94–29.28) | 1.06 | 0.92–1.22 | 0.442 |
| ITP vs. other, n (%) | 22/17 (56%) | 231/198 (54%) | 0.90 | 0.46–1.75 | 0.758 |
| US length of spleen, median cm (IQR) | 14.5 (12–18) | 13.5 (11–17) | 1.02 | 0.96–1.08 | 0.548 |
| Lowest preoperative platelets, median 103/mm3 (IQR) | 10 (2.5–21.5) | 8 (4–15) | 1.00 | 0.97–1.03 | 0.963 |
| Preoperative platelets, median 103/mm3 (IQR) | 69 (38–126) | 79.5 (50–120) | 1.00 | 0.99–1.01 | 0.695 |
| Need for extra method of preparing patients for LS, n (%) | 23 (58.97%) | 249 (58.04%) | 1.04 | 0.52–2.06 | 0.912 |
| Accessory spleen, n (%) | 7 (17.95%) | 66 (15.38%) | 1.20 | 0.51–2.85 | 0.673 |
| Technique, n (%) -vessels first -hilar transection |
17 (44.74%) 21 (55.26%) |
147 (35.34%) 269 (64.66%) |
0.68 | 0.234–1.32 | 0.251 |
| Operative time, median min (IQR) | 95 (75–120) | 100 (70–130) | 0.99 | 0.98–1.01 | 0.614 |
| Blood loss, median ml (IQR) | 100 (40–175) | 50 (20–100) | 1.01 | 1.00–1.02 | 0.003 |
| Conversion, n (%) | 1 (2.56%) | 13 (3.03%) | 0.84 | 0.11–6.64 | 0.870 |
| Intraoperative adverse events, n (%) | 5 (12.82%) | 20 (4.66%) | 3.01 | 1.06–8.54 | 0.038 |
| Year of surgery | 0.93 | 0.87–1.01 | 0.050 | ||
| Multivariate | |||||
| Blood loss ≥500 mL | 2.94 | 0.70–12.27 | 0.138 | ||
| Intraoperative adverse events | 1.00 | 0.99–1.02 | 0.210 | ||
IQR—interquartile range, OR—odds ratio, CI—confidence interval, BMI—body mass index, ITP—idiopathic trombocytopenia.