Table 7.
Risk factors for perioperative serious perioperative morbidity (Clavien–Dindo III–V).
| Parameter | Complicated | Non-Complicated | OR | 95% CI | p-Value |
|---|---|---|---|---|---|
| Difficult splenectomy, n (%) | 5 (8.93%) | 51 (91.07%) | 0.01 | 0.003–1.62 | 0.996 |
| No difficult splenectomy, n (%) | 18 (4.37%) | 394 (95.63%) | |||
| Age, median (IQR) | 47 (29–60) | 47 (29–59) | 0.99 | 0.97–1.02 | 0.964 |
| Males/Females, n (%) | 12/11 (52%/48%) | 161/284 (36%/64%) | 0.52 | 0.22–1.21 | 0.127 |
| BMI, median kg/m2 (IQR) | 27.51 (18.59–32.37) | 25.83 (22.94–29.32) | 1.01 | 0.86–1.19 | 0.913 |
| ITP vs. other, n (%) | 13/10 (57%/43%) | 240/205 (54%/46%) | 0.90 | 0.39–2.10 | 0.808 |
| US length of spleen, median cm (IQR) | 14.5 (12–17) | 14 (11–17) | 1.03 | 0.95–1.11 | 0.454 |
| Lowest preoperative platelets, median 103/mm3 (IQR) | 7 (1–12) | 8 (4–17) | 0.98 | 0.93–1.03 | 0.452 |
| Preoperative platelets, median 103/mm3 (IQR) | 59 (31–102) | 79.5 (50–120) | 0.99 | 0.98–1.00 | 0.246 |
| Need for extra method of preparing patients for LS, n (%) | 15 (65%) | 257 (58%) | 1.37 | 0.57–3.31 | 0.481 |
| Accessory spleen, n (%) | 5 (21.74%) | 68 (15.28%) | 1.54 | 0.55–4.30 | 0.408 |
| Technique, n (%) -vessels first -hilar transection |
7 (30.43%) 16 (69.57%) |
157 (36.43%) 274 (63.57%) |
1.31 | 0.53–3.26 | 0.561 |
| Operative time, median min (IQR) | 105 (80–120) | 100 (70–130) | 0.99 | 0.99–1.01 | 0.945 |
| Blood loss, median ml (IQR) | 100 (30–200) | 50 (20–100) | 1.01 | 1.00–1.02 | 0.029 |
| Conversion, n (%) | 0 | 14 (3.15%) | n/a | n/a | n/a |
| Intraoperative adverse events, n (%) | 3 (13.04%) | 22 (4.94%) | 2.88 | 0.79–10.48 | 0.107 |
| Year of surgery | 0.97 | 0.89–1.06 | 0.475 |
IQR—interquartile range, OR—odds ratio, CI—confidence interval, BMI—body mass index, ITP—idiopathic trombocytopenia, US—ultrasound.