Table 1.
Category | Human Fetus Risk | Drugs |
---|---|---|
A | No fetal risk | |
B | No risk of human fetus. Possible animal risk but human studies lacking. | Infliximab, Adalimumab, Golimumab, Certolizumab, Etanercept |
C | Human risk cannot be ruled out | Glucocorticoids, Cyclosporine, Tacrolimus, Azathioprine, Sirolimus, Everolimus, Rituximab, Eculizumab, Belimumab, Hydroxychloroquine |
D | Evidence of risk to human fetus | Mycophenolate, Cyclophos phamide, Chlorambucil, Bortezomib, Tyosine-kinase inhibitors |
X | Contraindication in pregnancy | Leflunomide, Methotrexate |