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. 2018 Dec 19;7(12):567. doi: 10.3390/jcm7120567

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Drug use: (a) Bar chart of HIPEC (hyperthermic intraperitoneal chemotherapy) reports (n = 171) with respective drugs or drug combinations. (b) Percentages of included reports on selected drugs and drug combinations plotted against HIPEC duration in minutes (x-axis). (c) Percentages of drugs and drug combinations among reports. (d) Percentages of drug mono- and combination therapies. Drug combinations were further subdivided into protocols using a drug combination with MMC or L-OHP. Abbreviations used: CDDP (cisplatin); DOX (doxorubicin); IRI (irinotecan); L-OHP (oxaliplatin); and MMC (mitomycin c).