Table 4.

Important idiosyncratic AEs

AE	Imatinib 400 mg daily*	Nilotinib 400 mg twice daily	Dasatinib 100 mg daily	Bosutinib 400 mg daily
Range of vascular events, %	1.1-2.5	15.9	4.7	1.5
Range of pleural effusions, %	0.8-1.9	0.7	28.0	1.5
Pulmonary hypertension, %	0.4	0.7	5.0	NR
Range of grade 3 to 4 diarrhea, %	<0.1-3.6	2.5	NR	7.8
Range of grade 3 to 4 abnormal liver function tests, %	2.9-4.2	18.5	NR	24.3

^*Frequencies differ slightly by trial.